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Interferon-beta-1b-induced short- and long-term signatures of treatment activity in multiple sclerosis

Interferon beta (IFNβ) reduces disease burden in relapsing-remitting multiple sclerosis (MS) patients. In this study, IFNβ-1b-treated MS patient gene expression profiles and biological knowledgebases were integrated to study IFNβ's pleiotropic mechanisms of action. Genes involved in immune regu...

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Main Authors: Croze, E, Yamaguchi, K D, Knappertz, V, Reder, A T, Salamon, H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793239/
https://ncbi.nlm.nih.gov/pubmed/22711062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2012.27
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