Bidirectional Transepithelial IgG Transport by a Strongly Polarized Basolateral Membrane Fcγ-Receptor

The human MHC class I–related neonatal Fc receptor, hFcRn, mediates bidirectional transport of IgG across mucosal barriers. Here, we find that at steady state hFcRn distributes predominantly to an apical intracellular compartment and almost exclusively to the basolateral cell surface of polarized ep...

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Autores principales: Claypool, Steven M., Dickinson, Bonny L., Wagner, Jessica S., Johansen, Finn-Eirik, Venu, Nanda, Borawski, Jason A., Lencer, Wayne I., Blumberg, Richard S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2004
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC379272/
https://ncbi.nlm.nih.gov/pubmed/14767057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0832
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