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In vitro synthesis of primary specific anti-breast cancer antibodies by normal human peripheral blood mononuclear cells

In this study, we developed a unique in vitro model to mimic the endogenous tumor microenvironment to understand the effect of immunotherapy with activated T-cells (ATC) armed with anti-CD3 × anti-Her2 bispecific antibody (aATC) on antibody response by naive immune cells. This model contained a co-c...

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Main Authors: Thakur, Archana, Norkina, Oxana, Lum, Lawrence G.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792712/
https://ncbi.nlm.nih.gov/pubmed/21713642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1056-9
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