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Design of a novel bilayered gastric mucoadhesive system for localized and unidirectional release of lamotrigine
Lamotrigine is a BCS class II drug with pH dependent solubility. The bilayered gastric mucoadhesive tablets of lamotrigine were designed such that the drug and controlled release polymers were incorporated in the upper layer and the lower layer had the mucoadhesive polymers. The major ingredients se...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3792623/ https://ncbi.nlm.nih.gov/pubmed/24109205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.01.004 |
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