Design of a novel bilayered gastric mucoadhesive system for localized and unidirectional release of lamotrigine

Lamotrigine is a BCS class II drug with pH dependent solubility. The bilayered gastric mucoadhesive tablets of lamotrigine were designed such that the drug and controlled release polymers were incorporated in the upper layer and the lower layer had the mucoadhesive polymers. The major ingredients se...

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Bibliographic Details
Main Authors: Mohana Raghava Srivalli, K., Lakshmi, P.K., Balasubramaniam, J.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792623/
https://ncbi.nlm.nih.gov/pubmed/24109205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.01.004
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