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Tumor Suppressor Activity of Profilin Requires a Functional Actin Binding Site

Profilin 1 (PFN1) is a regulator of the microfilament system and is involved in various signaling pathways. It interacts with many cytoplasmic and nuclear ligands. The importance of PFN1 for human tissue differentiation has been demonstrated by the findings that human cancer cells, expressing conspi...

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Hlavní autoři: Wittenmayer, Nina, Jandrig, Burkhard, Rothkegel, Martin, Schlüter, Kathrin, Arnold, Wolfgang, Haensch, Wolfgang, Scherneck, Siegfried, Jockusch, Brigitte M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC379259/
https://ncbi.nlm.nih.gov/pubmed/14767055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-12-0873
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