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Fine-tuning of neuronal architecture requires two profilin isoforms
Two profilin isoforms (PFN1 and PFN2a) are expressed in the mammalian brain. Although profilins are essential for regulating actin dynamics in general, the specific role of these isoforms in neurons has remained elusive. We show that knockdown of the neuron-specific PFN2a results in a significant re...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936622/ https://ncbi.nlm.nih.gov/pubmed/20798032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004406107 |
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