Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression

The histone methyltransferase EZH2 is a central epigenetic regulator of cell survival, proliferation, and cancer stem cell (CSC) function. EZH2 expression is increased in various human cancers, including highly aggressive pancreatic cancers, but the mechanisms underlying for its biologic effects are...

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Detalhes bibliográficos
Main Authors: Bao, Bin, Ali, Shadan, Banerjee, Sanjeev, Wang, Zhiwei, Logna, Farah, Azmi, Asfar S., Kong, Dejuan, Ahmad, Aamir, Li, Yiwei, Padhye, Subhash, Sarkar, Fazlul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792589/
https://ncbi.nlm.nih.gov/pubmed/22108826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2182
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