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Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer

BACKGROUND: The existence of cancer stem cells (CSCs) or cancer stem-like cells in a tumor mass is believed to be responsible for tumor recurrence because of their intrinsic and extrinsic drug-resistance characteristics. Therefore, targeted killing of CSCs would be a newer strategy for the preventio...

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Autori principali: Bao, Bin, Ali, Shadan, Kong, Dejuan, Sarkar, Sanila H., Wang, Zhiwei, Banerjee, Sanjeev, Aboukameel, Amro, Padhye, Subhash, Philip, Philip A., Sarkar, Fazlul H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052388/
https://ncbi.nlm.nih.gov/pubmed/21408027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017850
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