Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells

Ras gene is frequently mutated, and also associated with increased Ras expression and its GTPase activity (activity) in pancreatic cancer (PC), which could in part be due to deregulated expression of microRNAs (miRNAs) contributing to tumor aggressiveness. Here we report, for the first time, that Ra...

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Main Authors: Ali, Shadan, Ahmad, Aamir, Aboukameel, Amro, Bao, Bin, Padhye, Subhash, Philip, Philip A., Sarkar, Fazlul H.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326199/
https://ncbi.nlm.nih.gov/pubmed/22261338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.01.013
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