MC1R is a Potent Regulator of PTEN after UV Exposure in Melanocytes

The individuals carrying melanocortin-1-receptor (MC1R) variants, especially those associated with red hair color, fair skin and poor tanning ability (RHC-trait), are more prone to melanoma while the underlying mechanism is poorly defined. Here, we report that UVB exposure triggers PTEN interaction...

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Hauptverfasser: Cao, Juxiang, Wan, Lixin, Hacker, Elke, Dai, Xiangpeng, Lenna, Stefania, Jimenez-Cervantes, Celia, Wang, Yongjun, Leslie, Nick R., Xu, George X., Widlund, Hans R., Ryu, Byungwoo, Alani, Rhoda M., Dutton-Regester, Ken, Goding, Colin R., Hayward, Nicholas K., Wei, Wenyi, Cui, Rutao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792490/
https://ncbi.nlm.nih.gov/pubmed/23973372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.010
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