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Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast

We uncovered a novel role for the spliceosome in regulating mRNA expression levels that involves splicing coupled to RNA decay, which we refer to as spliceosome-mediated decay (SMD). Our transcriptome-wide studies identified numerous transcripts that are not known to have introns but are spliced by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Volanakis, Adam, Passoni, Monica, Hector, Ralph D., Shah, Sneha, Kilchert, Cornelia, Granneman, Sander, Vasiljeva, Lidia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792478/
https://ncbi.nlm.nih.gov/pubmed/24065768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.221960.113
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