Evaluation and critical assessment of putative MCL-1 inhibitors

High levels of BCL-2 family proteins are implicated in a failed/ineffective apoptotic programme, often resulting in diseases, including cancer. Owing to their potential as drug targets in cancer therapy, several inhibitors of BCL-2 family proteins have been developed. These primarily target specific...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Varadarajan, S, Vogler, M, Butterworth, M, Dinsdale, D, Walensky, L D, Cohen, G M
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2013
נושאים:
Original Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792441/
https://ncbi.nlm.nih.gov/pubmed/23832116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.79
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