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Studying Parents and Grandparents to Assess Genetic Contributions to Early-Onset Disease

Suppose DNA is available from affected individuals, their parents, and their grandparents. Particularly for early-onset diseases, maternally mediated genetic effects can play a role, because the mother determines the prenatal environment. The proposed maximum-likelihood approach for the detection of...

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Detalhes bibliográficos
Autor principal: Weinberg, Clarice R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC379235/
https://ncbi.nlm.nih.gov/pubmed/12533786
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