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Studying Parents and Grandparents to Assess Genetic Contributions to Early-Onset Disease
Suppose DNA is available from affected individuals, their parents, and their grandparents. Particularly for early-onset diseases, maternally mediated genetic effects can play a role, because the mother determines the prenatal environment. The proposed maximum-likelihood approach for the detection of...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society of Human Genetics
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC379235/ https://ncbi.nlm.nih.gov/pubmed/12533786 |
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