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Assessing the Cumulative Contribution of New and Established Common Genetic Risk Factors to Early-Onset Prostate Cancer

BACKGROUND: We assessed the evidence for association between 23 recently reported prostate cancer (PCa) variants and early-onset PCa and the aggregate value of 63 PCa variants for predicting early-onset disease using 931 unrelated men diagnosed with PCa prior to age 56 years and 1126 male controls....

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Lange, Ethan M., Ribado, Jessica V., Zuhlke, Kimberly A., Johnson, Anna M., Keele, Gregory R., Li, Jin, Wang, Yunfei, Duan, Qing, Li, Ge, Gao, Zhengrong, Li, Yun, Xu, Jianfeng, Zheng, S. Lilly, Cooney, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873425/
https://ncbi.nlm.nih.gov/pubmed/26671023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-0995
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