Dissection of a Krox20 positive feedback loop driving cell fate choices in hindbrain patterning

Although feedback loops are essential in development, their molecular implementation and precise functions remain elusive. Using enhancer knockout in mice, we demonstrate that a direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing ve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bouchoucha, Yassine X, Reingruber, Jürgen, Labalette, Charlotte, Wassef, Michel A, Thierion, Elodie, Desmarquet-Trin Dinh, Carole, Holcman, David, Gilardi-Hebenstreit, Pascale, Charnay, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792346/
https://ncbi.nlm.nih.gov/pubmed/24061538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.46
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados