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Hierarchical Modeling of Linkage Disequilibrum: Genetic Structure and Spatial Relations

Linkage disequilibrium (LD) mapping offers much promise for the positional cloning of disease-causing genes. However, conventional estimates of LD may fluctuate substantially across contiguous genomic regions, because of population-specific phenomena such as mutation, genetic drift, population struc...

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Bibliografiske detaljer
Main Authors: Conti, David V., Witte, John S.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC379228/
https://ncbi.nlm.nih.gov/pubmed/12525994
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