Major Recessive Gene(s) with Considerable Residual Polygenic Effect Regulating Adult Height: Confirmation of Genomewide Scan Results for Chromosomes 6, 9, and 12

Segregation and linkage analyses were performed for adult height in a population of 200 Dutch families, each of which was ascertained through a proband with asthma. The best-fit model from the segregation analysis was a major recessive gene with a significant residual polygenic background. Models wi...

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Publié dans:Am J Hum Genet
Auteurs principaux: Xu, Jianfeng, Bleecker, Eugene R., Jongepier, Hajo, Howard, Timothy D., Koppelman, Gerard H., Postma, Dirkje S., Meyers, Deborah A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2002
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC379200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12119602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1086/342216
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