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Differential Desensitization of Homozygous Haplotypes of the β(2)-Adrenergic Receptor in Lymphocytes

Single-nucleotide polymorphisms of the β(2)-adrenergic receptor gene and its 5′ promoter have been associated with differences in receptor function and desensitization. Linkage disequilibrium may account for inconsistencies in reported effects of isolated polymorphisms. Therefore, we have investigat...

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Autori principali: Oostendorp, Jaap, Postma, Dirkje S., Volders, Haukeline, Jongepier, Hajo, Kauffman, Henk F., Boezen, H. Marike, Meyers, Deborah A., Bleecker, Eugene R., Nelemans, S. Adriaan, Zaagsma, Johan, Meurs, Herman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718471/
https://ncbi.nlm.nih.gov/pubmed/15879418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200409-1162OC
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