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In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels – mirage or pot of gold?

The primary purpose of this review is to address the progress towards small molecule modulators of human Transient Receptor Potential Canonical proteins (TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7). These proteins generate channels for calcium and sodium ion entry. They are relevant to many mammali...

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Detalhes bibliográficos
Main Authors: Bon, Robin S, Beech, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791986/
https://ncbi.nlm.nih.gov/pubmed/23763262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12274
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