Bayesian refinement of association signals for 14 loci in 3 common diseases

To further investigate susceptibility loci identified by genome-wide association studies, we genotyped 5,500 SNPs across 14 associated regions in 8,000 samples from a control group and 3 diseases: type 2 diabetes (T2D), coronary artery disease (CAD) and Graves’ disease. We defined, using Bayes theor...

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Main Authors: Maller, Julian B, McVean, Gilean, Byrnes, Jake, Vukcevic, Damjan, Palin, Kimmo, Su, Zhan, Howson, Joanna M M, Auton, Adam, Myers, Simon, Morris, Andrew, Pirinen, Matti, Brown, Matthew A, Burton, Paul R, Caulfield, Mark J, Compston, Alastair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Hill, Adrian V S, Mathew, Christopher G, Pembrey, Marcus, Satsangi, Jack, Stratton, Michael R, Worthington, Jane, Craddock, Nick, Hurles, Matthew, Ouwehand, Willem, Parkes, Miles, Rahman, Nazneen, Duncanson, Audrey, Todd, John A, Kwiatkowski, Dominic P, Samani, Nilesh J, Gough, Stephen C L, McCarthy, Mark I, Deloukas, Panagiotis, Donnelly, Peter
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791416/
https://ncbi.nlm.nih.gov/pubmed/23104008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2435
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