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Estimating Diversifying Selection and Functional Constraint in the Presence of Recombination

Models of molecular evolution that incorporate the ratio of nonsynonymous to synonymous polymorphism (d(N)/d(S) ratio) as a parameter can be used to identify sites that are under diversifying selection or functional constraint in a sample of gene sequences. However, when there has been recombination...

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Detalhes bibliográficos
Main Authors: Wilson, Daniel J., McVean, Gilean
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456295/
https://ncbi.nlm.nih.gov/pubmed/16387887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.044917
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