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The Role of Cross-Chain Ionic Interactions for the Stability of Collagen Model Peptides

The contribution of ionic interactions to the stability of the collagen triple helix was studied using molecular dynamics (MD) simulations and biophysical methods. To this end, we examined the stability of a host-guest collagen model peptide, Ac-GPOGPOGPYGXOGPOGPO-NH(2), substituting KGE, KGD, EGK,...

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Detalhes bibliográficos
Main Authors: Keshwani, Neelam, Banerjee, Shounak, Brodsky, Barbara, Makhatadze, George I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791305/
https://ncbi.nlm.nih.gov/pubmed/24094409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.018
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