The Role of Cross-Chain Ionic Interactions for the Stability of Collagen Model Peptides

The contribution of ionic interactions to the stability of the collagen triple helix was studied using molecular dynamics (MD) simulations and biophysical methods. To this end, we examined the stability of a host-guest collagen model peptide, Ac-GPOGPOGPYGXOGPOGPO-NH(2), substituting KGE, KGD, EGK,...

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Hauptverfasser: Keshwani, Neelam, Banerjee, Shounak, Brodsky, Barbara, Makhatadze, George I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Proteins and Nucleic Acids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791305/
https://ncbi.nlm.nih.gov/pubmed/24094409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.018
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