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A TLR6 polymorphism is associated with increased risk of Legionnaires’ Disease

Legionella pneumophila (Lp), the etiologic agent of Legionnaires’ Disease (LD), is an important cause of community-acquired and nosocomial pneumonia. However, the host immune and genetic determinants of human susceptibility to Lp are poorly understood. Here we show that both TLR6 and TLR1 cooperate...

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Autores principales: Misch, Elizabeth Ann, Verbon, Annelies, Prins, Jan M., Skerrett, Shawn J., Hawn, Thomas Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791179/
https://ncbi.nlm.nih.gov/pubmed/23823019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.34
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