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ATM and the epigenetics of the neuronal genome

Ataxia-telangiectasia (A-T) is a neurodegenerative syndrome caused by the mutation of the ATM gene. The ATM protein is a PI3kinase family member best known for its role in the DNA damage response. While repair of DNA damage is a critical function that every CNS neuron must perform, a growing body of...

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Hlavní autor: Herrup, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791148/
https://ncbi.nlm.nih.gov/pubmed/23707635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2013.05.005
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