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Bidentate Ligands on Osmium(VI) Nitrido Complexes Control Intracellular Targeting and Cell Death Pathways

The cellular response evoked by anti-proliferating osmium(VI) nitrido compounds of general formula OsN(N^N)Cl(3) (N^N = 2,2′-bipyridine 1, 1,10-phenanthroline 2, 3,4,7,8-tetramethyl-1,10-phenanthroline 3, or 4,7-diphenyl-1,10-phenanthroline 4) can be tuned by subtle ligand modifications. Complex 2 i...

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Autors principals: Suntharalingam, Kogularamanan, Johnstone, Timothy C., Bruno, Peter M., Lin, Wei, Hemann, Michael T., Lippard, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791136/
https://ncbi.nlm.nih.gov/pubmed/24041161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4075375
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