Nuclear Factor κ-B Is Activated in the Pulmonary Vessels of Patients with End-Stage Idiopathic Pulmonary Arterial Hypertension

OBJECTIVES: To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic pulmonary arterial hypertension (PAH). BACKGROUND: Idiopathic PAH is a severe progressive disease characterized by pulmonary vascular remodeling and excessive proliferation of vascular ce...

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Hauptverfasser: Price, Laura C., Caramori, Gaetano, Perros, Frederic, Meng, Chao, Gambaryan, Natalia, Dorfmuller, Peter, Montani, David, Casolari, Paolo, Zhu, Jie, Dimopoulos, Konstantinos, Shao, Dongmin, Girerd, Barbara, Mumby, Sharon, Proudfoot, Alastair, Griffiths, Mark, Papi, Alberto, Humbert, Marc, Adcock, Ian M., Wort, S. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790752/
https://ncbi.nlm.nih.gov/pubmed/24124488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075415
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