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Evolutionary Origin of the Mitochondrial Cholesterol Transport Machinery Reveals a Universal Mechanism of Steroid Hormone Biosynthesis in Animals

Steroidogenesis begins with the transport of cholesterol from intracellular stores into mitochondria via a series of protein-protein interactions involving cytosolic and mitochondrial proteins located at both the outer and inner mitochondrial membranes. In adrenal glands and gonads, this process is...

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Detalhes bibliográficos
Main Authors: Fan, Jinjiang, Papadopoulos, Vassilios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790746/
https://ncbi.nlm.nih.gov/pubmed/24124589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076701
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