Ewing Sarcoma Cells Secrete EWS/Fli-1 Fusion mRNA via Microvesicles

Tumours defined as Ewing sarcoma (ES) constitute a group of highly malignant neoplasms that most often affect children and young adults in the first 2 decades of life. The EWS/Fli-1 fusion gene, a product of the translocation t(11;22) (q24; 12), is detected in 95% of ES patients. Recently, it was va...

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Detalhes bibliográficos
Main Authors: Tsugita, Masanori, Yamada, Nami, Noguchi, Shunsuke, Yamada, Kazunari, Moritake, Hiroshi, Shimizu, Katsuji, Akao, Yukihiro, Ohno, Takatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790721/
https://ncbi.nlm.nih.gov/pubmed/24124617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077416
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