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Understanding the Impact of 2D and 3D Fibroblast Cultures on In Vitro Breast Cancer Models

The utilization of 3D, physiologically relevant in vitro cancer models to investigate complex interactions between tumor and stroma has been increasing. Prior work has generally focused on the cancer cells and, the role of fibroblast culture conditions on tumor-stromal cell interactions is still lar...

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Detalhes bibliográficos
Main Authors: Sung, Kyung Eun, Su, Xiaojing, Berthier, Erwin, Pehlke, Carolyn, Friedl, Andreas, Beebe, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790689/
https://ncbi.nlm.nih.gov/pubmed/24124550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076373
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