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Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects
The transition of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) is a critical step in breast cancer progression. We introduce a simple microfluidic 3D compartmentalized system in which mammary epithelial cells (MCF-DCIS) are co-cultured with human mammary fibroblasts (HMFs), whi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094750/ https://ncbi.nlm.nih.gov/pubmed/21135965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ib00063a |
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