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Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

The transition of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) is a critical step in breast cancer progression. We introduce a simple microfluidic 3D compartmentalized system in which mammary epithelial cells (MCF-DCIS) are co-cultured with human mammary fibroblasts (HMFs), whi...

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Bibliografische gegevens
Hoofdauteurs: Sung, Kyung Eun, Yang, Ning, Pehlke, Carolyn, Keely, Patricia J, Eliceiri, Kevin W, Friedl, Andreas, Beebe, David J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094750/
https://ncbi.nlm.nih.gov/pubmed/21135965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ib00063a
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