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Asymmetric Catalysis at a Distance: Catalytic, Site-Selective Phosphorylation of Teicoplanin

We report three distinct, peptide-based catalysts that enable site-selective phosphorylation of three distinct hydroxyl groups within the complex glycopeptide antibiotic teicoplanin A(2)-2. Two of the catalysts are based on a design that capitalizes on a catalyst-substrate interaction that mimics th...

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Detalhes bibliográficos
Main Authors: Han, Sunkyu, Miller, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790668/
https://ncbi.nlm.nih.gov/pubmed/23924210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja406067v
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