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Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs
The generation of a series of analogs of Erythromycin A (EryA, 2) is described. In this study, we compared two peptide-based catalysts – one originally identified from a catalyst screen (5), and its enantiomer (ent-5) – for the selective functionalization of EryA. The semi-synthetic analogs were sub...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669672/ https://ncbi.nlm.nih.gov/pubmed/18819795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.019 |
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