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Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs

The generation of a series of analogs of Erythromycin A (EryA, 2) is described. In this study, we compared two peptide-based catalysts – one originally identified from a catalyst screen (5), and its enantiomer (ent-5) – for the selective functionalization of EryA. The semi-synthetic analogs were sub...

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Detalhes bibliográficos
Main Authors: Lewis, Chad A., Merkel, Janie, Miller, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669672/
https://ncbi.nlm.nih.gov/pubmed/18819795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.019
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