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Loss of MeCP2 function is associated with distinct gene expression changes in the striatum

Rett syndrome (RTT) is a neurodevelopmental disorder characterized by developmental regression beginning 6–18 months after birth, followed by a lifetime of intellectual disability, stereotyped behaviors, and motor deficits. RTT is caused by mutations in the gene encoding MeCP2, a methyl-CpG binding...

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Detalhes bibliográficos
Main Authors: Zhao, Ying-Tao, Goffin, Darren, Johnson, Brian, Zhou, Zhaolan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790640/
https://ncbi.nlm.nih.gov/pubmed/23948639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.08.001
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