Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells

BACKGROUND: Triple-negative breast cancer (TNBC) has significantly worse prognosis. Acquired chemoresistance remains the major cause of therapeutic failure of TNBC. In clinic, the relapsed TNBC is commonly pan-resistant to various drugs with completely different resistant mechanisms. Investigation o...

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Bibliographische Detailangaben
Hauptverfasser: Liu, P, Kumar, I S, Brown, S, Kannappan, V, Tawari, P E, Tang, J Z, Jiang, W, Armesilla, A L, Darling, J L, Wang, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790184/
https://ncbi.nlm.nih.gov/pubmed/24008666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.534
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