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Structural insights into substrate recognition in proton-dependent oligopeptide transporters

Short-chain peptides are transported across membranes through promiscuous proton-dependent oligopeptide transporters (POTs)—a subfamily of the major facilitator superfamily (MFS). The human POTs, PEPT1 and PEPT2, are also involved in the absorption of various drugs in the gut as well as transport to...

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Detalhes bibliográficos
Main Authors: Guettou, Fatma, Quistgaard, Esben M, Trésaugues, Lionel, Moberg, Per, Jegerschöld, Caroline, Zhu, Lin, Jong, Agnes Jin Oi, Nordlund, Pär, Löw, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790050/
https://ncbi.nlm.nih.gov/pubmed/23867627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.107
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