Structural insights into substrate recognition in proton-dependent oligopeptide transporters

Short-chain peptides are transported across membranes through promiscuous proton-dependent oligopeptide transporters (POTs)—a subfamily of the major facilitator superfamily (MFS). The human POTs, PEPT1 and PEPT2, are also involved in the absorption of various drugs in the gut as well as transport to...

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Main Authors: Guettou, Fatma, Quistgaard, Esben M, Trésaugues, Lionel, Moberg, Per, Jegerschöld, Caroline, Zhu, Lin, Jong, Agnes Jin Oi, Nordlund, Pär, Löw, Christian
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
Teme:
Scientific Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790050/
https://ncbi.nlm.nih.gov/pubmed/23867627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.107
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