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Interleukin-4 Induces Senescence in Human Renal Carcinoma Cell Lines through STAT6 and p38 MAPK
Interleukin (IL)-4, originally identified as a lymphocyte growth factor, can directly inhibit growth of certain tumor cell types. We reported previously that IL-4 induced cell cycle arrest in G(1) phase through an increase in p21(WAF1/CIP1) expression in human renal cell carcinoma (RCC) cell lines....
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789971/ https://ncbi.nlm.nih.gov/pubmed/23935100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.499053 |
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