Interleukin-4 Induces Senescence in Human Renal Carcinoma Cell Lines through STAT6 and p38 MAPK

Interleukin (IL)-4, originally identified as a lymphocyte growth factor, can directly inhibit growth of certain tumor cell types. We reported previously that IL-4 induced cell cycle arrest in G(1) phase through an increase in p21(WAF1/CIP1) expression in human renal cell carcinoma (RCC) cell lines....

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Autori principali: Kim, Hag Dong, Yu, Su-Jin, Kim, Hee Suk, Kim, Yong-Jin, Choe, Jeong Min, Park, Yun Gyu, Kim, Joon, Sohn, Jeongwon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789971/
https://ncbi.nlm.nih.gov/pubmed/23935100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.499053
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