Characterization of Two ENU-Induced Mutations Affecting Mouse Skeletal Morphology

Using the N-ethyl-N-nitrosourea (ENU) mutagenesis screen, we have identified two skeletal morphology mutants, Skm1 and Skm2. Positional cloning and candidate gene sequencing localized the causative point mutations within the genes coding for natriuretic peptide receptor C (NPR-C) and filamin b (FLNB...

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Autors principals: Dauphinee, Shauna M., Eva, Megan M., Yuki, Kyoko E., Herman, Melissa, Vidal, Silvia M., Malo, Danielle
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2013
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Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789799/
https://ncbi.nlm.nih.gov/pubmed/23979929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.007310
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