Suppression of Hepcidin Expression and Iron Overload Mediate Salmonella Susceptibility in Ankyrin 1 ENU-Induced Mutant

Salmonella, a ubiquitous Gram-negative intracellular bacterium, is a food borne pathogen that infects a broad range of hosts. Infection with Salmonella Typhimurium in mice is a broadly recognized experimental model resembling typhoid fever in humans. Using a N-ethyl-N-nitrosurea (ENU) mutagenesis re...

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Main Authors: Yuki, Kyoko E., Eva, Megan M., Richer, Etienne, Chung, Dudley, Paquet, Marilène, Cellier, Mathieu, Canonne-Hergaux, François, Vaulont, Sophie, Vidal, Silvia M., Malo, Danielle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563626/
https://ncbi.nlm.nih.gov/pubmed/23390527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055331
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