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The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense

Trypanosoma brucei gambiense causes 97% of all cases of African sleeping sickness, a fatal disease of sub-Saharan Africa. Most species of trypanosome, such as T. b. brucei, are unable to infect humans due to the trypanolytic serum protein apolipoprotein-L1 (APOL1) delivered via two trypanosome lytic...

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Библиографические подробности
Главные авторы: Capewell, Paul, Clucas, Caroline, DeJesus, Eric, Kieft, Rudo, Hajduk, Stephen, Veitch, Nicola, Steketee, Pieter C., Cooper, Anneli, Weir, William, MacLeod, Annette
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789759/
https://ncbi.nlm.nih.gov/pubmed/24098129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003686
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