Differences between Trypanosoma brucei gambiense Groups 1 and 2 in Their Resistance to Killing by Trypanolytic Factor 1

BACKGROUND: The three sub-species of Trypanosoma brucei are important pathogens of sub-Saharan Africa. T. b. brucei is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. T. b. rhodesiense and T. b. gambiense are able to resist lysis by TLF. Th...

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Bibliographic Details
Main Authors: Capewell, Paul, Veitch, Nicola J., Turner, C. Michael R., Raper, Jayne, Berriman, Matthew, Hajduk, Stephen L., MacLeod, Annette
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167774/
https://ncbi.nlm.nih.gov/pubmed/21909441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001287
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