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Genetically Engineered Frameshifted YopN-TyeA Chimeras Influence Type III Secretion System Function in Yersinia pseudotuberculosis

Type III secretion is a tightly controlled virulence mechanism utilized by many gram negative bacteria to colonize their eukaryotic hosts. To infect their host, human pathogenic Yersinia spp. translocate protein toxins into the host cell cytosol through a preassembled Ysc-Yop type III secretion devi...

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Библиографические подробности
Главные авторы: Amer, Ayad A. A., Costa, Tiago R. D., Farag, Salah I., Avican, Ummehan, Forsberg, Åke, Francis, Matthew S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789692/
https://ncbi.nlm.nih.gov/pubmed/24098594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077767
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