Genetically Engineered Frameshifted YopN-TyeA Chimeras Influence Type III Secretion System Function in Yersinia pseudotuberculosis

Type III secretion is a tightly controlled virulence mechanism utilized by many gram negative bacteria to colonize their eukaryotic hosts. To infect their host, human pathogenic Yersinia spp. translocate protein toxins into the host cell cytosol through a preassembled Ysc-Yop type III secretion devi...

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Autores principales: Amer, Ayad A. A., Costa, Tiago R. D., Farag, Salah I., Avican, Ummehan, Forsberg, Åke, Francis, Matthew S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789692/
https://ncbi.nlm.nih.gov/pubmed/24098594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077767
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