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A Medicinal Chemists’ Guide to Lead Optimization for Tuberculosis

Tuberculosis is a bacterial disease which predominantly affects the lungs and results in extensive tissue pathology. This pathology contributes to the complexity of drug development as it presents discrete microenvironments within which the bacterium resides, often under conditions where replication...

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Detalhes bibliográficos
Main Authors: Dartois, Véronique, Barry, Clifton E
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789655/
https://ncbi.nlm.nih.gov/pubmed/23910985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.07.006
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