Genetic Variation in IL18R1 and IL18 Genes and Inteferon γ ELISPOT Response to Smallpox Vaccination: An Unexpected Relationship

Background. Genetic association studies demonstrated a role for cytokine proteins and cytokine or cytokine receptor gene polymorphisms in smallpox vaccine–induced adaptive immunity. Methods. We examined the association of genetic polymorphisms with cellular (interferon [IFN] γ enzyme-linked immunosp...

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Bibliographic Details
Main Authors: Ovsyannikova, Inna G., Haralambieva, Iana H., Kennedy, Richard B., O'Byrne, Megan M., Pankratz, V. Shane, Poland, Gregory A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789570/
https://ncbi.nlm.nih.gov/pubmed/23901078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit341
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