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Genome-Wide Association Study of Antibody Response to Smallpox Vaccine

We performed a genome-wide association study (GWAS) of antibody levels in a multi-ethnic group of 1,071 healthy smallpox vaccine recipients. In Caucasians, the most prominent association was found with promoter SNP rs10489759 in the LOC647132 pseudogene on chromosome 1 (p=7.77 × 10(-8)). In African-...

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Detalhes bibliográficos
Main Authors: Ovsyannikova, Inna G., Kennedy, Richard B., O'Byrne, Megan, Jacobson, Robert M., Pankratz, V. Shane, Poland, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367131/
https://ncbi.nlm.nih.gov/pubmed/22542470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.04.055
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