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Accurate identification of polyadenylation sites from 3′ end deep sequencing using a naïve Bayes classifier
Motivation: 3′ end processing is important for transcription termination, mRNA stability and regulation of gene expression. To identify 3′ ends, most techniques use an oligo-dT primer to construct deep sequencing libraries. However, this approach can lead to identification of artifactual polyadenyla...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789547/ https://ncbi.nlm.nih.gov/pubmed/23962617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt446 |
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