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Trimeric Tau Is Toxic to Human Neuronal Cells at Low Nanomolar Concentrations
In Alzheimer's disease (AD), tau aggregates into fibrils and higher order neurofibrillary tangles, a key histopathological feature of AD. However, soluble oligomeric tau species may play a more critical role in AD progression since these tau species correlate better with neuronal loss and cogni...
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Päätekijät: | , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Hindawi Publishing Corporation
2013
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789488/ https://ncbi.nlm.nih.gov/pubmed/24159335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/260787 |
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